Professor William Gray
Director & Senior Research Leader
William (Liam) Gray is Professor of Functional Neurosurgery at Cardiff University and Honorary Consultant Neurosurgeon at the University Hospital of Wales.
He is Director of the Advanced NeuroTherapies Centre (ANTC), a Health & Care Research Wales funded research centre for the development and delivery of Advanced Therapies Medicinal Products (ATMPs) to the brain in early phase clinical trials. He is UK CI for the uniQure AMT-130 gene therapy trial for Huntington’s Disease, and PI for gene therapy trials in Fronto-Temporal Dementia (Aviadobio) and Parkinson’s Disease (AskBio).
As a surgeon neuroscientist, his clinicaI and research focus is on brain repair, either by cell replacement utilizing endogenous or transplanted neural precursor cells, or cellular reprogramming utilising gene or RNA therapies.
He leads active research groups studying the neuroinflammatory responses to ATMP delivery, developing surgical devices for cell and gene therapy delivery, and modelling therapy delivery using advanced MRI imaging. He currently co-leads the European Huntington’s Disease Network ATMP Working Group and chairs the Surgical Delivery Task Force.