NIHR Evidence Synthesis programme

This funding programme is newly open to Wales-based researchers

The Evidence Synthesis Programme funds research projects that identify, evaluate and combine data from existing research studies to provide best evidence, including on the effectiveness and cost-effectiveness of treatments, tests and other interventions, to support decision-making across health, public health and social care in all four nations of the UK.

The Evidence Synthesis Programme is funded by the NIHR, with contributions from the Chief Scientist Office (CSO) in Scotland, Health and Care Research Wales, and the HSC R&D Division, Public Health Agency in Northern Ireland.

Evidence syntheses combine data from multiple sources, most commonly from existing research studies, to provide an overall summary of current knowledge. 

Evidence syntheses should be based on systematic processes to identify and collate relevant evidence that meets pre-specified eligibility criteria and to minimise the influence of bias. Combining individual study results and considering differences can reduce uncertainty and help make sense of conflicting study findings.

Whatever kind of evidence synthesis is conducted, appropriate, rigorous and transparent methods must be used so the conclusions can be trusted.

The production of evidence synthesis is supported through two funding streams:

• Technology Assessment Review teams are funded to provide NICE with independent research to inform their guidance committees
• Evidence Synthesis Groups (ESGs) are funded to address knowledge gaps or to answer a specific need for the Programme’s healthcare, public health and social care stakeholders/audiences

More information and how to apply can be found on the National Institute for Health and Care Research website.