Other COVID-19 studies
COVIDSurg
This is a large, international, observational study that aims to determine the optimal timing of surgery following SARS-CoV-2 infection and to assess key global surgical indicators.
Open in: Cardiff and Vale University Health Board
COVIDSurg-Cancer
Outcomes of Elective Cancer Surgery during the COVID-19 Pandemic Crisis: An international, multicentre, observational cohort study.
Open in: Cardiff and Vale University Health Board
LOng COvid Multidisciplinary consortium: Optimising Treatments and services across the NHS (LOCOMOTION)
The study aims to create a “gold standard” approach for the treatment of Long COVID.
Open in: Cardiff and Vale University Health Board
ENLIST Vaccination sub-study
Covid-19 Immune Response and Vaccine Efficacy in Patients with Renal Disease and/or Transplantation.
Open in: Cardiff and Vale University Health Board
CANDID
Critical Care and Deployed nurses: the impact of COVID-19 on work-related stress.
Open in: Cardiff and Vale University Health Board
Safety & immunogenicity extension study for ChAdOx1 nCoV-19
Post-approval follow-up for the COV001 and 002 trials, to determine the long-term safety and character of immunological response to the ChAdOx1 nCoV-19 coronavirus vaccine.
Open in: Aneurin Bevan University Health Board
VROOM: Vaccine Response On/Off Methotrexate
A multi-centre randomised controlled trial examining the effects of temporarily suspending low-dose methotrexate treatment for two weeks after SARS-CoV-2 vaccine booster on vaccine response in immunosuppressed adults with inflammatory conditions, including a nested mechanistic sub-study.
Open in: Aneurin Bevan University Health Board, Cwm Taf Morgannwg University Health Board
PROTECT V - PROphylaxis for paTiEnts at risk of COVID-19 infecTion
The PROTECT clinical trial aims to enrol people with significantly reduced kidney function and/or receiving certain kinds of immunosuppressive medicines such as solid organ transplant recipients who are at particularly high risk of COVID-19 and its complications. Seeking to test the use of nasal nicolosamide treatment as a prophylactic measure that either might prevent the disease from occurring or may reduce the number of cases where the disease becomes serious or life-threatening.
Open in: Betsi Cadwaladr University Health Board, Cardiff and Vale University Health Board
Exploring that effects home working has on 999 telephone triage staff
Exploring that effects home working has on 999 telephone triage clinicians in response to Covid-19: A qualitative study.
Open in: Welsh Ambulance Services NHS Trust
CATCH on CBCT
Covid Associated Temporal CHanges (CATCH) on Cone-Beam CT in cancer patients.
Open in: Velindre University NHS Trust
Paediatric diabetes – onset and decompensation in the pandemic
Paediatric diabetes mellitus – onset and decompensation during the pandemic, is there a temporal association with Sars -CoV-2?
Open in: Cardiff and Vale University Health Board
PEACH
Procalcitonin: Evaluation of Antibiotics in COVID-19 Hospitalised patients.
Open in: Aneurin Bevan University Health Board
COVID-19 EARLY NOVEL LABORATORY INSIGHT STUDY - COVID-19 ENLIST
The COVID-19 ENLIST study first aims to make use of samples collected from patients with suspected COVID-19 at presentation to hospital.
Comparing the pattern of immune responses between treatment responders and non-responders will help identify mechanisms of treatment resistance. This is anticipated to support discovery of new treatments.
Open in: Cardiff and Vale University Health Board, Swansea Bay University Health Board
COVID-19 Emergency Response Assessment (CERA)
The study aims to assess the health outcomes of those front line doctors dealing with the COVID-19 outbreak. It will focus on doctors working in high impact areas, the emergency department, anaesthesia and intensive care medicine.
Closed in: Aneurin Bevan University Health Board, Betsi Cadwaladr University Health Board, Cwm Taf Morgannwg University Health Board, Hywel Dda University Health Board, Swansea Bay University Health Board
COVER: COvid-19 Vascular sERvice Study
Determining the impact of COVID-19 pandemic on the provision, practice and outcomes of vascular surgery
The COVER study will be a multi-centre prospective project of the modifications to the vascular service, condition management and outcomes of interventions during the COVID-19 pandemic.
Closed in: Aneurin Bevan University Health Board
Completed in: Cardiff and Vale University Health Board
PHIND study
Clinical Evaluation of a Point of Care (POC) assay to identify PHenotypes IN the Acute Respiratory Distress Syndrome
Open in: Aneurin Bevan University Health Board
Suspended in: Cardiff and Vale University Health Board
Co-VIDA: A digital wellbeing tool to assess the psychological impact of the COVID-19 pandemic on NHS healthcare professionals
Evidence suggests worsening of mental health in health workers reduces quality of care they provide and also promotes absenteeism or even resignations. Changes in mental health wellbeing during pandemics may be linked to specific risk or protective factors – and there is intrinsic value in understanding these. Recent work from China on health workers revealed elevated anxiety, depression, insomnia and trauma – however given the key differences in Chinese and UK health systems, and shortfalls in that study suggest new research should urgently be done in the UK to understand the impact of COVID on NHS and non-NHS health workers.
Closed in: Cwm Taf Morgannwg University Health Board, Powys Teaching Health Board,
Open in: Swansea Bay University Health Board
Long and short term effects of standard of care treatments for people with cancer
Immune checkpoint inhibitors (ICPI) are drugs that release cancer immunity. ICPI cause immune attack on normal organs resulting in immune related adverse events (IrAE) including bowel inflammation called immune related colitis (IR-colitis). We will describe the clinical and pathological features of IR-colitis, exploring a role for viruses including Epstein Barr virus (EBV) which lives harmlessly in most people. More broadly, the study will explore clinical, pathological and microbiological features associated with ICPI treatment, cancer control and IrAE.
Open in: Swansea Bay University Health Board
Complete in: Cwm Taf Morgannwg University Health Board
National COVID-19 Chest Imaging Database (NCCID) v1.0
NCCID aims to establish a national research database for all UK NHS Trusts to provide chest X-ray and CT images and associated clinical data for patients suspected of Covid-19 infection.
Open in: Cwm Taf Morgannwg University Health Board
PACE
The main aims of this study are to record how many of these patients have had COVID-19 previously, have an active infection or go on to develop COVID-19 whilst receiving treatment for their Acute Myeloid Leukaemia (AML).
Closed in: Cardiff and Vale University Health Board
A prospective non interventional study to evaluate the role of immune and inflammatory response in recipients of allogeneic haematopoietic stem cell transplantation (SCT) affected by severe COVID19 infection
The aim of the present study is to study the immunology/inflammatory response of patients who present with a severe COVID19 related disease after having received stem cell transplantation.
Closed in: Cardiff and Vale University Health Board
Coagulopathy associated with Covid 19 (CA-Covid19) A Multi-Centre observational study
In this retrospective-prospective: multicentre study, we will document the patient characteristics, presenting haematological parameters and associated comorbidities and their association with bleeding, thrombosis and mortality in patients admitted for hospital treatment. Determining the predictive value of patient characteristics and presenting laboratory measurements for clinical outcomes in these patients will allow us to optimise management of these patients in the future.
Open in: Cardiff and Vale University Health Board, Cwm Taf Morgannwg University Health Board
Closed in: Aneurin Bevan University Health Board
Characterisation of the Immune Response to SARS-CoV-2 Infection
To study how the virus SARS-CoV-2, more commonly called Coronavirus, affects the part of the body that fights infection, the immune system. This study will look at how the immune system responds to the virus and how it varies from person to person.
Closed in: Cwm Taf Morgannwg University Health Board
COVID-19, employment and health in Wales
This study aims to determine:
(1) The underlying prevalence of precarious employment in Wales
(2) The impact of precarious employment on individual and household health and wellbeing
(3) The impact of COVID-19 on employment security
(4) The impact of changes to employment on individual and household health
(5) The public perceptions of fair work
Closed in: Public Health Wales
COPE Study: COVID-19 in Older People
The study aim is to assess frailty and multi-morbidity in older patients admitted to hospital with a diagnosis of COVID -19. Also to correlate frailty with both short-term and long-term outcomes.
Open in: Betsi Cadwaladr University Health Board
Closed in: Aneurin Bevan University Health Board
Completed in: Cardiff and Vale University Health Board
Rapid-19: Rapid diagnostics, antibody testing and host response in children with COVID-19
Closed in: Cardiff and Vale University Health Board
Working with MS during COVID-19
Post-COVID-19 implications for the employment of people with Multiple Sclerosis
Open in: Cardiff and Vale University Health Board
Active monitoring of the Safety of a COVID-19 Vaccine Study
Post-authorisation active surveillance of the Safety of COVID-19 Vaccine AstraZeneca (AZD-1222) in the UK: A consortium study
Closed in: Cwm Taf Morgannwg University Health Board
Almitrine bismesylate in COVID-19
To determine whether administration of almitrine bismesylate can ameliorate hypoxaemia in Covid-19 and augment effectiveness of supplementary oxygen therapy and respiratory support
Open in: Cardiff and Vale University Health Board
Blood Markers for Identifying & Investigating Infection With COVID19 & Sepsis in Children (pSeP)
Study aims to conduct research in children under 18 admitted to intensive care unit.
Using a systems approach towards mapping the body's immune and metabolic responses to COVID-19 or related illnesses and compare with other sepsis like illnesses.
Open in: Cardiff and Vale University Health Board
Bystander Experiences of domestic violence and abuse during COVID-19
A Mixed Methods Study into Bystander Experience of Domestic Violence and Abuse during the COVID-19 Pandemic.
Closed in: Public Health Wales
CABINS
COVID-19 Contact Adherence to Self-isolation Behavioural Insights Survey (CABINS)
Closed in: Public Health Wales
CoolBonding Study
Impact of COVID-19 visiting restrictions on bonding, attachment and mental health of parents of babies cooled for hypoxic-ischaemic encephalopathy: multicentre prospective cohort study.
Closed in: Aneurin Bevan University Health Board, Cardiff and Vale University Health Board
CoPE-HCP: COVID19 and Physical and Emotional wellbeing of HCP
Effect of COVID-19 on immediate and mid-term physical, behavioural and mental health of healthcare professionals: A cohort study of doctor, nurses and other health care professionals
Closed in: Betsi Cadwaladr University Health Board
COVID SALES
Radiological assessment of the lung apices for abnormalities consistent with Sars-CoV-2 infection in acute stroke CT studies.
Closed in: Cardiff and Vale University Health Board
COVID19 DREAM Study
Covid19 Dried bloodspot Antibody Measurement (DREAM) study.
Open in: Cardiff and Vale University Health Board, Swansea Bay University Health Board
COVID-19: Learning lessons from the community-led response in Wales
Sustaining community-led action in recovery: learning lessons from the community response to COVID-19 in Wales.
Closed in: Public Health Wales
COVIDCLOT (Thrombogenicity in Acute Exacerbation of COPD)
Fibrin clot microstructural analysis in COVID-19; its effect on clinical outcome and response to dexamethasone therapy.
Open in: Swansea Bay University Health Board
COVIDTrach; A UK cohort study of tracheostomy in COVID-19 patients
COVIDTrach aims to assess the outcomes of tracheostomy in mechanically ventilated patients with COVID-19. The use of personal protective equipment and incidence of COVID-19 amongst operators is also recorded.
Closed in: Aneurin Bevan University Health Board, Betsi Cadwaladr University Health Board ,Cardiff and Vale University Health Board
COVIP: COVID-19 in very old intensive care patients
Clinical course and prognostic factors of COVID-19 infection in very old intensive care patients - A study being undertaken in the UK as part of a multicentre, multinational, observational study of the same name.
Closed in: Betsi Cadwaladr University Health Board
Determining Covid-19 Risk After Attending Hospital Appointments
Determining the Risk of Developing Symptomatic COVID-19 Infection After Attending Hospital Outpatient Clinic appointments.
Open in: Cardiff and Vale University Health Board
Experiences of early parenthood in and beyond the Coronavirus Pandemic
The challenges of parenthood into and beyond the Coronavirus pandemic/outbreak; An Investigation of Perinatal Mental Health: How can we Understand and Address this experience to Improve Service Delivery and the Mental Well-Being of Mothers, Infants and Families?
Closed in: Swansea Bay University Health Board
Completed in: Hywel Dda University Health Board
GCS-NeuroCOVID paediatric substudy
Global Consortium Study of Neurological Dysfunction in COVID-19 - paediatric substudy.
Closed in: Cardiff and Vale University Health Board
IMT as a post-COVID-19 recovery strategy
Inspiration for the future: Using inspiratory muscle training in post-COVID-19 rehabilitation.
Open in: Cardiff and Vale University Health Board, Hywel Dda University Health Board
Iota-Carrageenan spray for COVID-19 prophylaxis
Efficacy of Iota-Carrageenan spray prophylaxis for healthcare professionals treating COVID-19 patients – A double blind randomised placebo-controlled trial.
Open in: Swansea Bay University Health Board
METABRONA
Metabolic approaches to abolishing cytokine storm in COVID-19.
Open in: Swansea Bay University Health Board
MOMA_V1.0
Measurement of mouthwash anti-viral activity against COVID-19
Open in: Betsi Cadwaladr University Health Board
Closed in: Cwm Taf Morgannwg University Health Board
Completed in: Cardiff and Vale University Health Board
OnCovid
ONCOVID: natural history and outcomes of cancer patients during the COVID19 epidemic.
Open in: Velindre University NHS Trust
PECovid
Exploring the experiences of people with psychosis during the Covid-19 pandemic.
Open in: Betsi Cadwaladr University Health Board
Providing inpatient mental health care in the NHS during Covid-19
Providing inpatient mental health care in the NHS during Covid-19: A Foucauldian discourse analysis.
Open in: Betsi Cadwaladr University Health Board
Psychological Impact of COVID-19
Psychological impact of COVID- 19- pandemic and experience: An international survey.
Closed in: Cwm Taf Morgannwg University Health Board
Psychological Impact of COVID-19
The psychological impact of surviving an intensive care admission due to coronavirus disease 2019 (COVID-19) on patients in the United Kingdom.
Open in: Cardiff and Vale University Health Board, Cwm Taf Morgannwg University Health Board, Swansea Bay University Health Board
REGAIN
Rehabilitation Exercise and psycholoGical support After covid-19 InfectioN’ (REGAIN): a multi-centre randomised controlled trial.
Open in: Cardiff and Vale University Health Board, Hywel Dda University Health Board
Closed in: Aneurin Bevan University Health Board, Swansea Bay University Health Board
TERAVOLT - Thoracic cancERs international coVid 19 cOLlaboraTion
International registry on thoracic cancer patients with COVID-19.
Open in: Swansea Bay University Health Board, Velindre University NHS Trust
The COVID-19 Resilience Project
Studying the impact of COVID-19 on the NHS workforce to guide trauma-informed and psychologically-informed support provision.
Closed in: Cardiff and Vale University Health Board, Cwm Taf Morgannwg University Health Board, Velindre University NHS Trust
Transformation of eye care services in Wales
Transformation of eye care services in Wales; community eye care provision during COVID19 restrictions.
Open in: Cardiff and Vale University Health Board
Understanding vaccine uptake within NHS Wales staff
This project seeks to explore the barriers and facilitators for NHS staff receiving vaccinations.
Closed in: Cwm Taf Morgannwg University Health Board
Wales Covid-19 Well-being survey
Looking at levels of wellbeing and psychological distress in the Welsh population during the Covid-19 pandemic.
Open in: Hywel Dda University Health Board, Cwm Taf Morgannwg University Health Board, Swansea Bay University Health Board, Velindre University NHS Trust
'Walking in their Shoes' - The Development of Education Intervention
‘Walking in their Shoes’ – The Development of an Education Intervention on Empathy.
Closed in: Aneurin Bevan University Health Board
AspiFLu
A study assessing the incidence and pathogenesis of Invasive Aspergillosis in Intensive Care Patients with Severe Influenza (AspiFLu).
Open in: Cardiff and Vale University Health Board
Stories from “the field”
Stories from "the field": A narrative inquiry into the impact of a social prescribing model of care during the COVID 19 pandemic. Version 1.
Open in: Cwm Taf Morgannwg University Health Board